Related Experiment Video
Updated: Jul 11, 2026

Oncogene Expression Analysis with Alterations in pH in a Pancreatic Ductal Cell Line
Published on: April 11, 2025
Inflammation and cancer: an ancient link with novel potentials
S Perwez Hussain1, Curtis C Harris
1Laboratory of Human Carcinogenesis, National Cancer Institute, NIH, Bethesda, MD, USA.
Abstract:
Infection and chronic inflammation contribute to about 1 in 4 of all cancer cases. Mediators of the inflammatory response, e.g., cytokines, free radicals, prostaglandins and growth factors, can induce genetic and epigenetic changes including point mutations in tumor suppressor genes, DNA methylation and post-translational modifications, causing alterations in critical pathways responsible for maintaining the normal cellular homeostasis and leading to the development and progression of cancer. Recent discovery of an interaction between microRNAs and innate immunity during inflammation has further strengthened the association between inflammation and cancer.
Related Concept Videos
Psychoneuroimmunology: Diabetes and Cancer
Inflammation: Introduction
Cancer Vaccines
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Tumor Immunotherapy
Cancer Prevention
Some...
Cancer Prevention
Some...