Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Self-assembling phenylpropyl ether dendronized helical polyphenylacetylenes.

Virgil Percec1, Mihai Peterca, Jonathan G Rudick

  • 1Roy & Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104-6323, USA. percec@sas.upenn.edu

Chemistry (Weinheim an Der Bergstrasse, Germany)
|September 26, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Complex Cubic Liquid-Crystalline Phase Self-Organized from Five Differently Distorted Supramolecular Globular Dendrimers.

Journal of the American Chemical Society·2026
Same author

One-component ionizable amphiphilic Janus dendrimers as a delivery platform for efficient mRNA vaccine development.

Science advances·2026
Same author

Extraordinary Tolerance of the Cogwheel Mechanism of Helical Self-Organization to Structural Defects.

Journal of the American Chemical Society·2025
Same author

Structural complexity driven by liquid-liquid crystal phase separation of smectics.

Soft matter·2025
Same author

Harnessing the Electron-Withdrawing Inductive Effect of One-Component Ionizable Amphiphilic Janus Dendrimers Unveils Cation-π Interactions and Their Important Roles to Targeted mRNA Delivery.

Journal of the American Chemical Society·2025
Same author

Targeted delivery of TGF-β mRNA to murine lung parenchyma using one-component ionizable amphiphilic Janus Dendrimers.

Nature communications·2025
Same journal

Pressure-Related Challenges and Strategic Approaches in Lithium Metal Sulfide all-Solid-State Batteries.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Dual Regulatory Functions of Classical Zinc Finger Clusters from Myeloid Zinc Finger-1.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same journal

A Selectfluor-based Polonovski Rearrangement Leading to Novel Entities for Synthetic and Medicinal Applications.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Relay Approach: A Convergent Synthesis of Key Fragments en route to (+)-Neosorangicin A.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Working Under Pressure: Empirical Findings on the Challenges Facing PhD Students in Chemistry.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
Same journal

Charge Resonance Interaction in Aromatic Trimer Radical Cations Revealed by IR Spectroscopy: The Case of Pyrrole Homo- and Heterotrimers.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026
See all related articles

Researchers report the first self-assembling phenylpropyl ether dendronized polymer, poly(10), which exhibits a stable right-handed helical structure. This helical polymer self-organizes into distinct lattices, demonstrating thermoreversible structural transitions.

Area of Science:

  • Polymer Chemistry
  • Supramolecular Chemistry
  • Materials Science

Background:

  • Dendronized polymers offer unique structural and functional properties.
  • Polyphenylacetylenes (PPAs) are known for their high cis-content and potential for helical structures.
  • Controlling polymer chirality is crucial for advanced material applications.

Purpose of the Study:

  • To synthesize and characterize the first self-assembling phenylpropyl ether-based dendronized polymer.
  • To determine the helical handedness and stability of the synthesized polymer.
  • To investigate the bulk self-organization and thermoreversible behavior of the dendronized polymer.

Main Methods:

  • Synthesis of dendronized polymer poly(10) and its nondendritic analogue poly(8) using [Rh(nbd)Cl]2/NEt3 catalyst.

Related Experiment Videos

  • Circular Dichroism (CD) spectroscopy to determine helical handedness via exciton chirality.
  • X-ray diffraction and microscopy to study bulk self-organization and lattice structures.
  • Differential Scanning Calorimetry (DSC) to analyze thermoreversible transitions.

    • Main Results:

    • The successful synthesis of a high-cis-content dendronized polyphenylacetylene, poly(10).
    • Determination of a preferred right-handed helical structure for poly(10) based on negative exciton chirality in CD spectra.
    • Observation of self-organization into Phiioh and Phih lattices, with a thermoreversible transition linked to cis-cisoidal to cis-transoidal isomerization.
    • Proposed model of interdigitating dendrons in adjacent strata for space-filling in the helical structure.

    Conclusions:

    • A novel self-assembling, right-handed helical dendronized polymer has been developed.
    • The polymer exhibits stable helical chirality and undergoes thermoreversible structural changes in bulk.
    • The findings provide insights into the design and self-organization of chiral dendronized polymers for potential applications.