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Updated: Feb 16, 2026

An In Vitro Approach to Photodynamic Therapy
Published on: August 17, 2018
Choroidal neovascularization following photodynamic therapy in a patient with chronic central serous
A Yaman1, G Arikan, A O Saatci
1Department of Ophthalmology, Dokuz Eylul University, Izmir, Turkey.
Purpose:
To present the clinical features and treatment of subfoveal choroidal neovascularization complicating photodynamic treatment (PDT) performed for chronic central serous chorioretinopathy (CSC).
Method:
A 48-year-old healthy woman who had chronic visual deterioration in her right eye due to chronic CSC was treated with standard PDT protocol.
Results:
Three weeks after the initial PDT, she experienced recovery in her vision and neurosensory detachment subsided clinically. However, six weeks after the PDT she returned with decreased visual acuity and metamorphopsia in the right eye. Fluorescein angiogram and optic coherence tomography delineated a classic subfoveal subretinal neovascular membrane. PDT was reperformed two more times, three months apart and closure of neovascular membrane was obtained.
Conclusion:
Choroidal neovascularization might have occurred during the natural course of disease process or as a consequence of PDT. PDT seems to be effective for treating the choroidal neovascularization complicating PDT performed for CSC.
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