Carotid arterial dissection as a cause of severe brain infarction in young adults
H Haapaniemi1, O Salonen, M Hillbom
1Department of Neurology, University of Oulu, Oulu, Finland.
Insights
Cervicocerebral arterial dissection is a rare cause of stroke in young adults, often linked to trauma or headache. Prompt imaging is recommended for suspected cases.
Area of Science:
- Neurology
- Vascular Medicine
- Radiology
Background:
- Cervicocerebral arterial dissection is a significant cause of stroke in young adults.
- Understanding the specific etiological factors and optimal diagnostic timing is crucial.
Purpose of the Study:
- To investigate the incidence of cervicocerebral arterial dissection in young adults presenting with first-ever stroke.
- To examine the relationship between stroke etiology, angiography timing, and dissection diagnosis.
Main Methods:
- Retrospective analysis of 184 young stroke patients (16-49 years) admitted between 1983-1990.
- Analysis of angiography timing relative to stroke onset (78% performed >1 week post-stroke).
Main Results:
- Carotid arterial dissection identified in 19% of patients; no vertebral dissections found.
- High mortality (26%) associated with carotid dissection-related ischemic stroke.
- Delayed angiography correlated with lower dissection detection rates and increased negative findings.
Conclusions:
- Prompt cervicocerebral artery imaging is advised for patients with preceding trauma or symptoms of headache/neck pain.
- Early diagnosis and intervention may improve outcomes for dissection-related strokes.
Objectives:
To investigate the occurrence of cervicocerebral arterial dissection in young adults, we examined the etiology of first-ever brain infarction and the timing of angiography.
Methods:
One hundred eighty-four subjects with first stroke aged 16 to 49 years, admitted to the Helsinki University Hospital between 1983 and 1990 were included. Seventy-eight percent of the angiographies were performed more than 1 week after the onset of stroke symptoms.
Results:
We identified 19 (10%) subjects with carotid arterial dissection and none with vertebral arterial dissection. Mortality attributed to ischemic stroke caused by carotid arterial dissection was high (26%). With longer time between onset of stroke symptoms and angiography, dissection was a rarer finding (P < .01), and there were more angiographies with no findings (P < .05). Trauma (P < .001) and headache (P < .05) preceded onset of stroke more frequently in these patients than in others.
Conclusions:
Prompt imaging of the cervicocerebral arteries is indicated if the patient has preceding trauma or complains of headache and/or neck pain.
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