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Updated: Jul 11, 2026

Transient Middle Cerebral Artery Occlusion Model of Stroke
Published on: August 11, 2023
Olfactory and taste dysfunction after bilateral middle cerebral artery stroke.
1Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Impaired smell and taste after stroke is rare. This case study highlights a patient with sensory dysfunction following an insular stroke, suggesting cortical integration areas may be involved.
Area of Science:
- Neurology
- Neuroscience
- Sensory Science
Background:
- Acquired olfactory and gustatory dysfunction are typically linked to orbitofrontal tumors or head trauma.
- Dysfunction of smell and taste following ischemic stroke is infrequently documented.
Purpose of the Study:
- To report a rare case of smell and taste impairment after an ischemic stroke.
- To explore the potential neurological basis for sensory dysfunction post-stroke.
Main Methods:
- Case report of a patient experiencing olfactory and gustatory deficits.
- Neuroimaging analysis to identify the stroke's location and extent.
- Correlation of clinical symptoms with neuroanatomical findings.
Main Results:
- The patient presented with impaired sense of smell and taste.
- A localized insular frontoparietal stroke was identified.
- A similar, mirror-image infarction was present in the contralateral hemisphere.
Conclusions:
- Localized insular strokes can lead to acquired smell and taste dysfunction.
- Injury to cortical areas integrating smell and taste may cause these sensory deficits.
- This case expands the understanding of stroke-related sensory impairments.
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