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Related Experiment Video

Updated: Jul 11, 2026

Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound

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The LightWire technology for catheter-based interventions.

Ran Kornowski¹, Hylton I Miller, Rona Shofti

¹Rabin Medical Center, Petach Tikva, Israel. rkornowski@clalit.org.il

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions

|September 27, 2007

Summary

The new LightWire guidewire uses opto-acoustic technology for accurate coronary imaging during angioplasty. It demonstrated reliable vessel measurements and maneuverability in animal trials, showing promise for guiding procedures.

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Area of Science:

Cardiovascular Imaging
Medical Device Technology

Background:

A novel opto-acoustic coronary imaging guidewire, LightWire, has been developed.
Designed for angioplasty, it provides real-time lumen and vessel wall dimension data.

Purpose of the Study:

Evaluate the maneuverability, device compatibility, and vessel measurement accuracy of the LightWire guidewire.
Confirm sensing capabilities and performance in coronary arteries.

Main Methods:

In vitro models and animal trials were conducted to assess device performance.
Focused on maneuverability, compatibility with other catheterization equipment, and vessel measurements.

Main Results:

In vitro validation of measurement capabilities.
Successful demonstration of coronary and peripheral artery diameter measurements, including stented vessels, in a pig model.
The LightWire maintained easy navigation and compatibility with other devices, acquiring accurate multi-location diameter measurements.

Conclusions:

Miniaturized opto-acoustic technology integrated into a guidewire can enhance coronary imaging.
The LightWire device shows potential as a diagnostic and guidance tool for coronary and peripheral angioplasty.