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[Mediastinal lymph nodes during the course of a metastatic prostate cancer]

A Roca Edreira1, C Aguilera Tubet, A Villanueva Peña

  • 1Servicio de Urología, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria. anroed@ono.com

Actas Urologicas Espanolas
|September 28, 2007
PubMed

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Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...