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Updated: Jul 11, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions
Published on: April 23, 2021
Correlation of diastolic blood pressure and signs of cognitive dysfunction in essential hypertension
H Goldman1, K M Kleinman, M Y Snow
1Neuropsychology Laboratory, Veterans Administration Hospital, Jefferson Barracks Division, St. Louis, Missouri 63125, USA.
Abstract:
A significant positive relationship was obtained between degree of diastolic hypertension and frequency of errors made on a psychological test sensitive to cognitive dysfunction in a sample of essential hypertensives. The significance of the relationship, (a) was obtained in spite of a small sample size and (b) persisted even after the possible confounding variables of age and IQ were statistically eliminated. These findings imply that essential hypertension may result in cognitive impairment as well as damage to other organ systems.
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