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PAI-1 as a target in kidney disease

Yufeng Huang1, Nancy A Noble

  • 1Fibrosis Research Laboratory, Division of Nephrology, Department of Medicine, University of Utah School of Medicine, Salt Lake City, UT 84108, USA.

Current Drug Targets
|September 28, 2007
PubMed
Summary

New therapies are needed to halt the progression of fibrotic kidney diseases. Targeting Plasminogen Activator Inhibitor-1 (PAI-1) offers a promising approach to combat chronic kidney disease by blocking its fibrogenic effects.

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