Management of ventricular tachycardia in the absence of structural heart disease

Ventricular tachycardia most often arises from the ventricular outflow tracts in patients with apparently structurally normal hearts, and is often termed idiopathic ventricular tachycardia. These tachycardias are characterized by a left bundle branch block, inferior axis QRS morphology, and a unique electropharmacologic profile. The choice of treatment is dictated by the severity of symptoms, and ranges from observation for asymptomatic patients, to antiarrhythmic agents for those who are mildly to moderately symptomatic (eg, palpitations), to catheter-based ablation for those with more troubling symptoms or those who develop tachycardia-mediated cardiomyopathy. Antiarrhythmic therapy can be effective for arrhythmia suppression, and radiofrequency ablation has a high success rate (> 90%) with few procedural complications. In general, ventricular outflow tract tachycardia has a favorable prognosis. Exclusion of arrhythmogenic right ventricular dysplasia/cardiomyopathy is important due to significant disparities in prognosis and treatment.