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Surgical Models of Gastroesophageal Reflux with Mice

Surgical Models of Gastroesophageal Reflux with Mice

Published on: August 25, 2015

Treatment options in pediatric GERD.

Neelesh A Tipnis¹, Colin D Rudolph

¹Neelesh A. Tipnis, MD Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA. ntipnis@mcw.edu

Current Treatment Options in Gastroenterology

|September 28, 2007

Summary

Gastroesophageal reflux disease (GERD) in children requires careful evaluation and treatment. Acid-suppression therapy is common for GERD, but its goals and risks must be weighed before use.

Area of Science:

Pediatric Gastroenterology
Infant Health
Digestive Disorders

Background:

Gastroesophageal reflux (GER) is a normal physiological process in infants and children.
When GER causes symptoms or complications, it is termed gastroesophageal reflux disease (GERD).
GERD necessitates specific diagnostic approaches and therapeutic interventions.

Purpose of the Study:

To outline the evaluation and management of GERD in pediatric populations.
To emphasize the importance of judicious pharmacologic treatment for GERD.
To discuss the considerations surrounding acid-suppression therapy and surgical options.

Main Methods:

Review of current clinical practices and literature regarding GERD in children.
Analysis of the role of acid-suppression therapy in managing GERD symptoms.

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Evaluation of the indications and limitations of surgical interventions for GERD.

Main Results:

Acid-suppression therapy is the primary pharmacological approach for GERD.
Careful consideration of treatment objectives and potential adverse effects of acid suppression is crucial.
Surgical treatment for GERD in children has a limited scope.

Conclusions:

Effective management of pediatric GERD involves targeted evaluation and appropriate treatment strategies.
Pharmacological treatment, particularly acid suppression, should be used judiciously, balancing benefits against risks.
The role of surgery in GERD management is currently restricted.