Related Experiment Video
Updated: Jul 11, 2026

Quantification of Acanthamoeba spp. Motility
Published on: September 20, 2024
Early diagnosis of amoebic keratitis due to a mixed infection with Acanthamoeba and Hartmannella
Jacob Lorenzo-Morales1, Enrique Martínez-Carretero, Ninive Batista
1University Institute of Tropical Diseases and Public Health of the Canary Islands, University of La Laguna, Avda. Astrofísico Fco. Sánchez, S/N, 38203, La Laguna, Tenerife, Canary Islands, Spain. jmlorenz@ull.es
Abstract:
A mixed keratitis due to Acanthamoeba and Hartmannella species is reported. The patient was a soft contact lens wearer. Early diagnosis was achieved by polymerase chain reaction and culture. The pathogenic potential of the isolated amoebae was proven using cytotoxicity assays. The reported case underlines the difficulties in identifying a corneal amoebic infection. In our case, the early diagnosis of a mixed infection allowed a proper antiamoebic treatment in an early stage of infection. This may have been the reason of a successful outcome after therapy.
Related Concept Videos
Amebiasis
Cryptococcal Meningitis
Trichomoniasis
