Dental rehabilitation of the patient with multiple endocrine neoplasia Type 2b

Multiple endocrine neoplasia 2b (MEN 2b) is characterized by medullary thyroid carcinoma, pheochromocytoma, and various neuromas throughout the body, including the oral cavity and the perioral and periocular areas. The syndrome is inherited in an autosomal dominant fashion with high penetrance. This article presents a case of MEN 2b in a 24-year-old woman and discusses the medical and surgical issues that relate to the disorder. In addition, this article describes the workup, diagnosis, and treatment, along with a discussion of the pathophysiology of MEN 2b as it relates to the dental rehabilitation of a patient with the disorder.