Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Step-Growth Polymers: Polyesters01:20

Types of Step-Growth Polymers: Polyesters

The introduction of polyesters has brought major development to the textile industry. The wrinkle-free behavior of polyester blends has eliminated the need for starching and ironing clothes.
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the polymer...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Air pollutant monitoring in different brick kiln technologies: a step towards the implication of emission inventory development of Punjab, Pakistan.

Environmental monitoring and assessment·2025
Same author

Robust and Operationally Simple Synthesis of Poly(bis(2,2,2-trifluoroethoxy) phosphazene) with Controlled Molecular Weight, Low PDI, and High Conversion.

ACS macro letters·2022
Same author

Amoebicidal Activity of Poly-Epsilon-Lysine Functionalized Hydrogels.

Investigative ophthalmology & visual science·2022
Same author

Novel Crosslinking System for Poly-Chloroprene Rubber to Enable Recyclability and Introduce Self-Healing.

Polymers·2021
Same author

Characterization of Tunable Poly-ε-Lysine-Based Hydrogels for Corneal Tissue Engineering.

Macromolecular bioscience·2021
Same author

Amplified fluorescence quenching in high ionic strength media.

Soft matter·2020

Related Experiment Video

Updated: Jul 11, 2026

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets
13:42

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets

Published on: November 2, 2011

Novel non-PEG derived polyethers as solid supports. 2. Solid-phase synthesis studies.

Gabriel Cavalli1, Andrew G Shooter, David A Pears

  • 1Department of Chemistry, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.

Journal of Combinatorial Chemistry
|September 29, 2007
PubMed
Summary

New polymer-supported synthesis resins, SLURPS (Superior Liquid Uptake Resins for Polymer-supported Synthesis), offer high loading capacities and excellent solvent compatibility. These novel resins enable efficient synthesis of peptides and other organic molecules, even in polar solvent mixtures.

More Related Videos

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
05:15

Solid-phase Synthesis of [4.4] Spirocyclic Oximes

Published on: February 6, 2019

A Simple and Efficient Protocol for the Catalytic Insertion Polymerization of Functional Norbornenes
09:08

A Simple and Efficient Protocol for the Catalytic Insertion Polymerization of Functional Norbornenes

Published on: February 27, 2017

Related Experiment Videos

Last Updated: Jul 11, 2026

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets
13:42

Solid-phase Submonomer Synthesis of Peptoid Polymers and their Self-Assembly into Highly-Ordered Nanosheets

Published on: November 2, 2011

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
05:15

Solid-phase Synthesis of [4.4] Spirocyclic Oximes

Published on: February 6, 2019

A Simple and Efficient Protocol for the Catalytic Insertion Polymerization of Functional Norbornenes
09:08

A Simple and Efficient Protocol for the Catalytic Insertion Polymerization of Functional Norbornenes

Published on: February 27, 2017

Area of Science:

  • Polymer Chemistry
  • Organic Synthesis
  • Materials Science

Background:

  • Solid-phase synthesis relies on polymer supports for efficient chemical transformations.
  • Existing polymer supports often have limitations in solvent compatibility and loading capacity.

Purpose of the Study:

  • To introduce and evaluate novel polyether resins, SLURPS, for polymer-supported synthesis.
  • To assess the performance of SLURPS in terms of loading capacity, solvent compatibility, and synthetic utility.

Main Methods:

  • Synthesis of amino-functionalized SLURPS resins (SLURPS-NH2).
  • Evaluation of resin loading capacity (up to 8.5 mmol/g).
  • Application in solid-phase synthesis of Leu-Enkephalin and aromatic carboxylic acids.
  • Demonstration of solvent compatibility using biphasic dihydroxylation and oxime synthesis/removal in polar solvent mixtures.
  • Reaction monitoring using gel-phase NMR and FTIR.

Main Results:

  • SLURPS-NH2 resins achieved high loading capacities.
  • Successful synthesis of Leu-Enkephalin with purity comparable to commercial resins.
  • High yields for loading and cleavage of aromatic carboxylic acids.
  • Demonstrated excellent solvent compatibility with polar mixtures (e.g., t-BuOH/water, ethanol/water).
  • Facilitated biphasic reactions and synthesis/removal of bound oximes.

Conclusions:

  • SLURPS resins are highly effective for polymer-supported synthesis, particularly with polar solvents and reagents.
  • They offer superior loading levels compared to standard amphiphilic resins with similar solvent compatibility.
  • SLURPS represent a promising new class of materials for advanced organic synthesis.