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Updated: Jul 11, 2026

Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology
Published on: August 23, 2024
Use of solid-supported liquid-liquid extraction in the analysis of polyphenols in wine
Frederico Nave1, Maria João Cabrita, Cristina Teixeira da Costa
1Departamento de Química da Universidade de Evora, Rua Romão Ramalho no. 59, 7000-617 Evora, Portugal.
Abstract:
Solid-supported liquid-liquid extraction (SS-LLE) was compared to liquid-liquid extraction (LLE) for the analysis of phenolic compounds in wine. Diatomaceous earth commercial cartridges were evaluated together with "in-house" made cartridges for the wine phenolic extraction. Statistical treatment, analysis of variance ANOVA-single factor, was used to compare the extraction yields obtained by these methods, and for the majority of the studied compounds, significantly higher yields were obtained by the SS-LLE methodology using the "in-house" prepared cartridges. This is an environmentally friendly low-cost sample preparation method which proved to be reproducible (RSD<5% for the most compounds) and yielding high recoveries (80-100%) for the compounds studied.
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