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[Jaundices in pregnancy].

M P Sánchez-Fayos1, C Hernández Guío

  • 1Fundación Jiménez Díaz, Universidad Autónoma de Madrid.

Revista Espanola De Enfermedades Digestivas
|August 1, 1991
PubMed
Summary

Jaundice in pregnancy stems from liver disease, hemolytic disorders, or pregnancy-related issues like cholestasis and hepatic steatosis. Severe eclampsia and postpartum hypercoagulability can also cause jaundice.

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Area of Science:

  • Obstetrics and Gynecology
  • Hepatology
  • Hematology

Context:

  • Pregnancy presents unique physiological changes that can affect liver function and predispose to jaundice.
  • Jaundice during pregnancy requires careful differential diagnosis due to various potential causes.
  • Understanding these causes is crucial for timely and appropriate management.

Purpose:

  • To categorize and describe the spectrum of disorders causing jaundice in pregnant individuals.
  • To differentiate between pre-existing, co-existing, and pregnancy-specific conditions leading to jaundice.
  • To highlight the potential severity and complications associated with jaundice in pregnancy.

Summary:

  • Jaundice in pregnancy can arise from pre-existing liver diseases (hepatitis, cirrhosis), hemolytic disorders, or conditions directly linked to gestation.
  • Pregnancy-specific causes include intrahepatic cholestasis, hyperemesis gravidarum with jaundice, and hepatic steatosis.
  • Severe eclampsia can cause jaundice of both hemolytic and parenchymal origin, while postpartum hypercoagulability may lead to Budd-Chiari syndrome.

Impact:

  • Provides a comprehensive overview for clinicians managing jaundice in pregnant patients.
  • Facilitates accurate diagnosis and targeted treatment strategies.
  • Emphasizes the importance of recognizing severe forms like eclampsia and Budd-Chiari syndrome for improved maternal outcomes.

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