Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Functional imaging studies in cannabis users.

Linda Chang1, Edward P Chronicle

  • 1Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96813, USA.LChang@hawaii.edu

The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry
|September 29, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The 30<sup>th</sup> Scientific Conference of the Society on NeuroImmune Pharmacology in Annapolis, Maryland, May 3<sup>rd</sup> - 6<sup>th</sup>, 2026.

NeuroImmune pharmacology and therapeutics·2026
Same author

Integrating AI Literacy into Medical Education: Preparing Future Clinicians for an AI-Driven Healthcare System.

Medical science educator·2026
Same author

Exploring health care learners' perceptions of AI integration in the curriculum: a survey tool and findings.

BMC medical education·2026
Same author

Resting-state functional connectivity in HIV - Findings from the ENIGMA HIV working group.

Psychiatry research. Neuroimaging·2026
Same author

Social Determinants of Health and Pediatric Long COVID in the US.

JAMA pediatrics·2026
Same author

Association Between Gas-Free Cerebrovascular Reactivity (CVR) and Cognitive Function in Older Adults With a High Risk for Vascular Dementia.

Journal of magnetic resonance imaging : JMRI·2025
Same journal

SNAREopathy in Neurologic Disorders: From Synaptic Mechanisms to Genetic and Epigenetic Regulation.

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry·2026
Same journal

Nonclustered Protocadherins in Autism: Integrating Cell Adhesion and Activity-Dependent Signalling.

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry·2026
Same journal

Brain-on-a-Chip and Blood-Brain Barrier-on-a-Chip Modeling for Neurodegenerative Disorders: Recent Progress.

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry·2026
Same journal

The Left Ventral Premotor Cortex: Powerful Roles in Reading.

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry·2026
Same journal

The 3-Body Problem: How Astrocytes May Govern Plasticity.

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry·2026
Same journal

Perisynaptic Astrocytic Processes as Communication Hubs and Early Sites of Dysfunction.

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry·2026
See all related articles

Neuroimaging studies reveal that delta-9-tetrahydrocannabinol (THC) acutely increases brain activation. Chronic cannabis use shows neuroadaptations in cognitive networks, but long-term effects remain uncertain.

Area of Science:

  • Neuroscience
  • Psychopharmacology

Background:

  • Cannabis is the most prevalent illicit drug in the U.S.
  • Understanding its neurological impact is crucial.

Purpose of the Study:

  • To review neuroimaging findings in cannabis users.
  • To assess acute and chronic effects of cannabis on brain function.

Main Methods:

  • Review of Positron Emission Tomography (PET) studies on acute delta-9-tetrahydrocannabinol (THC) effects.
  • Analysis of functional magnetic resonance imaging (fMRI) studies on chronic cannabis users.

Main Results:

  • Acute THC administration increases activation in frontal, paralimbic, and cerebellar regions.
  • Chronic cannabis use is associated with neuroadaptations in brain networks supporting cognition.

Related Experiment Videos

  • Evidence for structural brain changes in chronic users is equivocal.

    • Conclusions:

    • Acute THC effects align with observed behavioral changes.
    • Long-term consequences of chronic cannabis use on brain function require further investigation, especially in adolescents.
    • Reversibility of neuroadaptations with abstinence is undetermined.