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Chemometrics in pharmaceutical analysis.

J C Berridge1, P Jones, A S Roberts-McIntosh

  • 1Analytical Chemistry Department, Pfizer Central Research, Sandwich, Kent, UK.

Journal of Pharmaceutical and Biomedical Analysis
|January 1, 1991
PubMed
Summary
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Chemometric principles are revolutionizing pharmaceutical analysis. This review covers recent advances in spectrophotometry, chromatography, and expert systems for drug analysis.

Area of Science:

  • Analytical Chemistry
  • Pharmaceutical Sciences

Background:

  • Traditional pharmaceutical analysis methods are evolving.
  • Chemometrics offers advanced data analysis for complex pharmaceutical datasets.

Purpose of the Study:

  • To review recent advancements in chemometrics for pharmaceutical analysis.
  • To highlight the application of chemometrics in spectrophotometry, chromatography, and expert systems.

Main Methods:

  • Literature review of recent chemometric applications in pharmaceutical analysis.
  • Focus on spectrophotometry, chromatography, and expert systems.

Main Results:

  • Chemometric principles are increasingly integrated into pharmaceutical analysis.
  • Recent advances show significant improvements in analytical accuracy and efficiency.

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  • Expert systems offer novel approaches to data interpretation.
  • Conclusions:

    • Chemometrics is driving a paradigm shift in pharmaceutical analysis.
    • The integration of chemometrics enhances the capabilities of spectrophotometry and chromatography.
    • Expert systems represent a key area for future development in drug analysis.