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Published on: June 2, 2014
Cluster headache attacks and multiple sclerosis.
Salvatore Gentile1, Margherita Ferrero, Giovanna Vaula
1Neurology II - Headache Centre, Department of Neuroscience, University of Turin, Via Cherasco 15, I-10126, Torino, Italy. sgentile@molinette.piemonte.it
Cluster headache attacks in a patient resolved after methylprednisolone treatment for multiple sclerosis (MS). This case highlights the importance of neuroimaging for cluster headache patients to rule out structural lesions.
Area of Science:
- Neurology
- Neuroimmunology
Background:
- Cluster headache is a primary headache disorder.
- Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system.
Observation:
- A patient presented with typical cluster headache attacks.
- The patient was concurrently diagnosed with multiple sclerosis.
- Headache attacks resolved following intravenous methylprednisolone treatment.
Findings:
- Magnetic Resonance (MR) imaging revealed a pontine demyelinating lesion.
- The lesion involved the trigeminal nerve root inlet area ipsilateral to the headache pain.
- This case represents a rare association between cluster headache and MS.
Implications:
- The co-occurrence of cluster headache and MS is infrequently reported.
- This case underscores the utility of neuroimaging in evaluating cluster headache.
- Neuroimaging can help exclude structural lesions in patients with cluster headache.
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