Related Experiment Video
Updated: Jul 11, 2026

Microfluidic Model of Necrotizing Enterocolitis Incorporating Human Neonatal Intestinal Enteroids and a Dysbiotic Microbiome
Published on: July 28, 2023
Ischemic intestinal necrosis in a five-year-old girl with diabetic ketoacidosis
Mahmoud Ashrafi1, Mahin Hashemipour, Mohammad-Hassan Moadab
1Department of Pediatric Surgery, Alzahra Hospital, School of Medicine, Isfahan University of Medical Science, Isfahan, Iran. ashrafi@med.mui.ac.ir
Abstract:
Diabetic ketoacidosis is a major source of morbidity and mortality in children and adolescents with type I diabetes mellitus. Although diabetic ketoacidosis is often associated with dehydration and electrolyte disturbances, cases with gastrointestinal tract complications due to shock remain particularly unusual. Herein, we reported on a five-year-old girl who had severe diabetic ketoacidosis complicated by hypovolemic shock. Her abdominal pain and acidosis despite vigorous fluid resuscitation and insulin therapy failed to improve. Further investigations showed intestinal problem. At laparatomy gangrenous bowel--about 20 cm long--near the distal ileum was found. Entrectomy and ileo-jejunal anastomosis was done and the child survived.
Related Concept Videos
Diabetic Ketoacidosis ll: Pathophysiology
Diabetic Ketoacidosis l: Introduction
Intestinal Obstruction II: Pathophysiology
Intestinal Obstruction I: Introduction
Complications of Diabetes Mellitus
Pyloric Obstruction

