Inferring cellular networks--a review
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Updated: Jul 11, 2026

JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics
Published on: October 19, 2021
Florian Markowetz1, Rainer Spang
1Max Planck Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany. florian@genomics.princeton.edu
Abstract:
In this review we give an overview of computational and statistical methods to reconstruct cellular networks. Although this area of research is vast and fast developing, we show that most currently used methods can be organized by a few key concepts. The first part of the review deals with conditional independence models including Gaussian graphical models and Bayesian networks. The second part discusses probabilistic and graph-based methods for data from experimental interventions and perturbations.
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