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Related Concept Videos

Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
Incomplete Dominance01:43

Incomplete Dominance

Gregor Mendel's work (1822 - 1884) was primarily focused on pea plants. Through his initial experiments, he determined that every gene in a diploid cell has two variants called alleles inherited from each parent. He suggested that amongst these two alleles, one allele is dominant in character and the other recessive. The combination of alleles determines the phenotype of a gene in an organism.
Polygenic Traits01:18

Polygenic Traits

When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...
Polygenic Traits01:18

Polygenic Traits

When more than one gene is responsible for a given phenotype, the trait is considered polygenic. Human height is a polygenic trait. Studies have uncovered hundreds of loci that influence height, and there are believed to be many more. Due to the high number of genes involved, as well as environmental and nutritional factors, height varies significantly within a given population. The distribution of height forms a bell-shaped curve, with relatively few individuals in the population at the...

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Related Experiment Video

Updated: Jul 11, 2026

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
14:56

Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies

Published on: May 6, 2022

Genetics of obesity.

J Alfredo Martínez1, Alfredo Martínez-Hernández, Luís Enríquez

  • 1Department of Physiology and Nutrition, University of Navarra, 31008 Pamplona, Spain. jalfmtz@unav.es

Public Health Nutrition
|November 21, 2007
PubMed
Summary

Obesity arises from an energy imbalance, influenced by both genetic predispositions and environmental factors like diet and activity. Understanding gene-nutrient interactions is key to managing this complex health issue.

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Area of Science:

  • Genetics
  • Metabolism
  • Nutritional Science

Background:

  • Obesity stems from a sustained positive energy balance.
  • Rising obesity rates are linked to lifestyle changes, not genetic shifts.
  • Obesity is a complex disease involving the failure of body weight homeostasis.

Purpose of the Study:

  • To review and update advancements in the genetics of obesity.
  • To explore gene-nutrient interactions in energy balance regulation.
  • To discuss current nutri-genomic research methods.

Main Methods:

  • Analysis of recent investigations on energy balance regulation.
  • Interpretation of studies on gene-nutrient interactions.
  • Review of current nutri-genomic research methodologies.

Main Results:

  • Genetic factors contribute to obesity susceptibility.
  • Obesity can result from genetic deregulation (e.g., transcription, protein function).
  • Environmental exposures (diet, physical activity) play a significant role.

Conclusions:

  • Obesity is fundamentally an interaction between genetic and environmental factors.
  • Understanding genetic influences is crucial for managing obesity.