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Related Concept Videos

Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

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Related Experiment Video

Updated: Jul 11, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Using a stroke database to develop an optimal vascular imaging protocol for ischemic stroke.

Kamakshi Lakshminarayan1, David C Anderson, Raymond A Gensinger

  • 1Department of Neurology, University of Minnesota, Minneapolis, Minnesota 55455, USA. laksh004@umn.edu

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
|October 2, 2007
PubMed
Summary
This summary is machine-generated.

For diagnosing ischemic stroke, cervical and intracranial magnetic resonance angiography (CIMRA) is more cost-effective than carotid ultrasound. CIMRA provides better diagnostic yield for stroke mechanism evaluation.

Related Experiment Videos

Last Updated: Jul 11, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Area of Science:

  • Neurology
  • Radiology
  • Health Economics

Background:

  • Diagnosing ischemic stroke requires effective imaging of cervicocranial vasculature.
  • Multiple imaging sequences exist, necessitating optimization for cost and diagnostic accuracy.

Purpose of the Study:

  • To determine an optimal sequence of vascular imaging studies for ischemic stroke diagnosis.
  • To minimize costs while maximizing diagnostic yield using stroke database data.

Main Methods:

  • Comparison of two vascular imaging protocols using patient data from a stroke database.
  • Protocol 1: Carotid ultrasound first for anterior circulation strokes, followed by MRI angiography if needed.
  • Protocol 2: Cervical and intracranial magnetic resonance angiography (CIMRA) as the initial investigation for all strokes.

Main Results:

  • Protocol 1 mean cost: $702 per patient.
  • Protocol 2 mean cost: $679 per patient.
  • Protocol 2 identified tandem lesions and collateral variations missed by Protocol 1.

Conclusions:

  • CIMRA as the initial imaging strategy is more cost-effective ($679 vs $702) for acute ischemic stroke evaluation in this patient population.
  • This cost-effectiveness is dependent on local imaging costs and patient demographics.
  • Protocol 2 offers superior diagnostic information for stroke mechanism compared to a carotid ultrasound-first approach.