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Published on: February 10, 2023
Blood pressure control in hypertensive patients with a history of stroke
Yuko Ohta1, Takuya Tsuchihashi, Setsuro Ibayashi
1Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Insights
Hypertensive patients with a history of stroke showed lower diastolic blood pressure (BP) and higher rates of strict BP control (<130/85 mm Hg) compared to those without stroke history. This suggests increased physician awareness for BP management in stroke survivors.
Area of Science:
- Cardiology
- Neurology
- Hypertension Research
Background:
- Optimal blood pressure (BP) targets for hypertensive patients with a history of stroke are not well-defined.
- Hypertension is a major risk factor for stroke, necessitating effective BP management strategies.
Purpose of the Study:
- To assess the current status of BP control in hypertensive patients with a history of stroke.
- To compare clinical characteristics and BP control between hypertensive patients with and without a history of stroke.
Main Methods:
- A retrospective analysis of 413 hypertensive patients visiting a specialized clinic.
- Comparison of clinical characteristics and BP measurements (averaged from two occasions in 2002) between patients with and without stroke history (including infarction, TIA, hemorrhage).
- BP was measured using a mercury sphygmomanometer; strict BP control defined as <130/85 mm Hg.
Main Results:
- Patients with stroke history had significantly lower diastolic BP (76 vs 82 mm Hg) but similar systolic BP compared to those without stroke history.
- The rate of strict BP control (<130/85 mm Hg) was significantly higher in stroke patients (35.8%) than in non-stroke patients (19.8%).
- Antihypertensive drug classes used were similar, with calcium antagonists being most frequent; diuretics and beta-blockers were less common in ischemic stroke patients.
Conclusions:
- Hypertensive patients with a history of stroke exhibited lower BP levels and achieved stricter BP control in an outpatient setting.
- This may indicate heightened physician awareness and adherence to BP management guidelines for stroke prevention and secondary prevention.
- Further research is warranted to confirm optimal BP targets for this high-risk population.
Abstract:
The targets for lowering blood pressure (BP) in hypertensive stroke patients remain unclear. We assessed the current status of BP control in hypertensive patients with a history of stroke, investigating 413 hypertensive patients (age range, 19 to 93; mean age, 62 +/- 12 years) who visited the hypertension and stroke clinic at Kyushu University Hospital. We compared the clinical characteristics of these hypertensive patients with a history of stroke, including brain infarction, transient ischemic attack, and brain hemorrhage (age range, 29-86; mean age, 66 +/- 12 years; n = 95) with those of patients without such a history (age range, 19-93; mean age, 61 +/- 12 years; n = 318). Clinic BP was measured by physicians with a mercury sphygmomanometer, and the averaged BP determined at 2 occasions in 2002 was used for analysis. Systolic BP was similar among the patients with and without a history of stroke (134 +/- 15 vs 137 +/- 14 mm Hg; P = not significant), but diastolic BP was significantly lower in patients with stroke than in those without stroke (76 +/- 10 vs 82 +/- 10 mm Hg; P < .05). When strict BP control was defined as <130/85 mm Hg, the rate of strict BP control was higher in the stroke patients than in those without stroke (35.8% vs 19.8%; P < .01). The average number of antihypertensive drug classes used was similar in the 2 groups (1.7 +/- 0.9 and 1.8 +/- 1.0, respectively). Calcium antagonists were the most frequently used drugs in both groups. Diuretics and beta-blockers were prescribed less frequently to the patient with ischemic stroke than to those without stroke. BP levels were lower in the patients with brain hemorrhage than in those with lacunar and atherothrombotic infarction. In our outpatient clinic, BP levels were lower in the stroke patients than in the patients without stroke, which may reflect physicians' awareness of the importance of strict BP control in stroke patients, as has been suggested by several recent clinical intervention trials.
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