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Updated: Jul 11, 2026
High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022
Brief communications: visualization of coronary arteries in rats by 3-dimensional real-time contrast echocardiography
Fuminobu Ishikura1, Hideo Hirayama, Akiko Iwata
1School of Allied Health Sciences, Osaka University, Faculty of Medicine, Osaka, Japan. ishikura@sahs.med.osaka-u.ac.jp
Abstract:
Angiogenesis is under intense investigation to advance the treatment of various ischemic diseases. Small animals, such as mice and rats, are often used for this purpose. However, evaluating the structure of coronary arteries in small animals in situ is not easy. We succeeded in visualizing the coronary artery in rats on 3-dimensional real-time contrast echocardiography using a high-frequency transducer. These methods will be applied for more convenient assessment in a new study, examining issues such as angiogenesis using rats in situ.
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