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Observational Study Protocol for Repeated Clinical Examination and Critical Care Ultrasonography Within the Simple Intensive Care Studies
Published on: January 16, 2019
Cubicin Outcomes Registry and Experience (CORE) methodology.
Kenneth V I Rolston1, John Segreti, Kenneth C Lamp
1M. D. Anderson Cancer Center, University of Texas, Houston, Texas, USA.
The American Journal of Medicine
|October 16, 2007
Summary
The Cubicin Outcomes Registry and Experience (CORE) study analyzed real-world daptomycin use in 1,160 patients. It provides early insights into daptomycin
Area of Science:
- Pharmacology and Infectious Diseases
- Clinical Pharmacy and Practice
Background:
- Daptomycin is a critical antibiotic for treating Gram-positive infections.
- Understanding real-world usage patterns is essential for optimizing therapy.
Purpose of the Study:
- To describe the initial post-marketing clinical experience with daptomycin.
- To collect data on patient demographics, infections, treatments, and outcomes.
Main Methods:
- Retrospective data collection using standardized case report forms.
- Involved 45 institutions across the United States.
- Data gathered from November 2003 to December 2004.
Main Results:
- Collected data on 1,160 patients receiving daptomycin.
- Included information on patient demographics, infection types, and treatment regimens.
- Outcomes were assessed at the conclusion of daptomycin therapy.
Conclusions:
- The CORE registry offers valuable insights into the early clinical application of daptomycin.
- This data aids in understanding real-world daptomycin utilization and patient responses.
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