Kimura's disease occurred in the whole arm

Kimura's disease is a rare, chronic inflammatory disease of unknown etiology. It occurs commonly in head and neck. We present a rare case of Kimura's disease that occurred widely in the whole arm. A 17-year-old man presented with 5 years history of palpable non-tender mass in the antero-medial aspect of the upper arm. Blood investigations showed a peripheral eosinophilia and the elevation of IgE. Coronal and sagittal T1 and T2 images showed the multiple lobulated, and well-demarcated masses in the subcutaneous layer. On histological assessment, it was noted that within the subcutaneous fat there was an ill-defined non-encapsulated proliferation of lymphoid follicles with focal eosinophilic folliculolysis. The lymph nodes showed numerous prominent lymphoid follicles with florid germinal centers, follicular hyperplasia and massive perinodal eosinophilic infiltration.