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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Antiasthma Drugs: β2-Adrenoceptor Agonists01:25

Antiasthma Drugs: β2-Adrenoceptor Agonists

Bronchodilators are critical in managing asthma, a chronic respiratory condition characterized by airway constriction due to inflammation and hyper-reactivity. Specifically, bronchodilators ease this constriction by relaxing the bronchial muscles, facilitating easier breathing.
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce relaxation in these...
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...

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Updated: Jul 11, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

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Published on: November 4, 2010

Sodium and asthma: something borrowed, something new?

Simon A Hirota1, Luke J Janssen

  • 1Smooth Muscle Research Group, University of Calgary, Calgary, Alberta, Canada.

American Journal of Physiology. Lung Cellular and Molecular Physiology
|October 2, 2007
PubMed
Summary

Sodium

Area of Science:

  • Pulmonary Medicine
  • Cardiovascular Research
  • Cell Physiology

Background:

  • Early research suggested a link between sodium intake and airway diseases, but findings were inconclusive.
  • Recent advances include understanding salt sensitivity in hypertension and the Na+/Ca2+ exchanger's role in smooth muscle.
  • These developments offer new perspectives on sodium's impact on respiratory health.

Purpose of the Study:

  • To review recent advancements in understanding sodium's role in hypertension and smooth muscle function.
  • To apply these insights to the context of airway smooth muscle and asthma.
  • To clarify the potential contribution of sodium to airway-related diseases.

Main Methods:

  • Literature review of recent developments in hypertension research.

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Acupuncture in a Rat Model of Asthma
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Last Updated: Jul 11, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

Acupuncture in a Rat Model of Asthma
07:14

Acupuncture in a Rat Model of Asthma

Published on: August 25, 2020

  • Literature review of the Na+/Ca2+ exchanger's function in smooth muscle.
  • Application of these findings to airway smooth muscle physiology and asthma.

    • Main Results:

    • Improved understanding of salt sensitivity in hypertension identifies specific patient subgroups.
    • The Na+/Ca2+ exchanger is crucial for regulating smooth muscle contraction and relaxation.
    • These mechanisms are relevant to airway smooth muscle function and asthma pathophysiology.

    Conclusions:

    • Sodium's role in airway diseases warrants further investigation, particularly in salt-sensitive individuals.
    • The Na+/Ca2+ exchanger may represent a novel therapeutic target for asthma.
    • Integrating cardiovascular and respiratory research provides a more comprehensive view of sodium's systemic effects.