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Related Concept Videos

Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...

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Updated: Jul 11, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
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Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

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Tuberculosis of the thymus.

Mauro Tadeu Ajaj Saieg1, Fabíola del Carlo Bernardi, Roberto Gonçalves

  • 1Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brasil. maurosaieg@yahoo.com

Jornal Brasileiro De Pneumologia : Publicacao Oficial Da Sociedade Brasileira De Pneumologia E Tisilogia
|October 2, 2007
PubMed
Summary

Tuberculosis of the thymus is an extremely rare cause of mediastinal masses. This case highlights the importance of considering thymic tuberculosis in the differential diagnosis of anterior mediastinal lesions.

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A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
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A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection
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A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Published on: October 5, 2015

Area of Science:

  • Pathology
  • Radiology
  • Clinical Medicine

Background:

  • Anterior mediastinal masses are a heterogeneous group, with thymoma, germ cell tumors, and lymphomas being the most common.
  • Tuberculosis of the thymus is exceptionally rare, usually involving mediastinal lymph nodes.

Observation:

  • An 18-year-old patient presented with acute thoracic pain and dyspnea, with imaging revealing a large anterior mediastinal mass.
  • Surgical excision of the mass was performed for diagnosis and treatment.

Findings:

  • Microscopic examination showed significant inflammation and granulomas within the thymic tissue.
  • Positive Ziehl-Neelsen staining confirmed the presence of acid-fast bacilli, establishing a diagnosis of tuberculosis.

Implications:

  • This case underscores the necessity for surgeons and pathologists to consider thymic tuberculosis in the differential diagnosis of mediastinal masses.
  • Early recognition and appropriate management are crucial for patients presenting with these rare conditions.