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Acute transverse myelitis secondary to Salmonella paratyphi B infection

A Pourhassan1, M M Shoja, R S Tubbs

  • 1Tuberculosis and Lung Disease Research Center, Tabriz Medical University, Tabriz, Iran.

Infection
|October 2, 2007
PubMed

Insights

Acute transverse myelitis (ATM), a rare spinal cord inflammation, can be triggered by Salmonella infections. This case highlights successful antibiotic treatment for ATM secondary to Salmonella paratyphi B, suggesting broader Salmonella species as potential causes.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Immunology

Background:

  • Acute transverse myelitis (ATM) is a rare neurological disorder characterized by spinal cord inflammation and demyelination.
  • The parainfectious form, often linked to preceding infections, is the most common presentation of ATM.
  • Salmonella typhi infection has been rarely associated with ATM, but Salmonella paratyphi B has not been previously reported.

Observation:

  • A case report details a woman who developed ATM following infection with Salmonella paratyphi B (paratyphoid fever).
  • The patient's ATM was successfully treated with parenteral antibiotics targeting the Salmonella infection.
  • This presentation suggests a potential link between Salmonella paratyphi B and ATM.

Findings:

  • This is the first reported case of ATM secondary to Salmonella paratyphi B infection.
  • The findings support the consideration of Salmonella species as a potential trigger for ATM.
  • Successful antibiotic therapy indicates a treatable etiology for this specific type of ATM.

Implications:

  • Clinicians should consider ATM in the differential diagnosis of neurological complications following Salmonella infections.
  • Early diagnosis and targeted antibiotic treatment may improve outcomes for patients with infection-associated ATM.
  • Further research is warranted to explore the mechanisms and prevalence of ATM associated with Salmonella species.

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