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Minimising treatment-associated risks in systemic cancer therapy
Ulrich Jaehde1, Andrea Liekweg, Sven Simons
1Institute of Pharmacy, Department of Clinical Pharmacy, University of Bonn, Rheinische Friedrich-Wilhelms-Universitaet Bonn, An der Immenburg 4, 53121 Bonn, Germany. u.jaehde@uni-bonn.de
Drug-related problems (DRPs) are common in cancer therapy. Pharmacists play a crucial role in minimizing risks through pharmaceutical care, enhancing patient safety in oncology.
Area of Science:
- Oncology
- Pharmacology
- Clinical Pharmacy
Background:
- Systemic cancer therapy presents significant potential for drug-related problems (DRPs) due to high toxicity and complex regimens.
- Common DRPs include adverse effects, drug-drug interactions, medication errors, and non-adherence.
Purpose of the Study:
- To review the consequences of DRPs in systemic cancer therapy.
- To identify the pharmacist's specific contributions to minimizing treatment-associated risks.
Main Methods:
- Searches were conducted in PubMed, Embase, and the Cochrane Library.
- Bibliographies of retrieved articles were examined for additional references.
- Included studies were published in English between 1980 and 2007.
Main Results:
- Pharmacists are actively involved in assuring quality and safety in cancer therapy.
- Oncology pharmacy has emerged as a specialized discipline.
- Pharmaceutical care concepts aim to address DRPs by coordinating pharmacist activities.
Conclusions:
- Pharmaceutical care for cancer patients requires development within research projects.
- Integration into disease management programs is essential for broad implementation of pharmaceutical care.
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