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Embryo Transfer Surgery via Laparotomy in Gilts

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Timing intra-Fallopian transfer procedures.

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¹IVF Unit, Department of Obstetrics and Gynecology, Wolfson Medical Centre, Holon 58100. a_w@zahav.net.il

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Summary

This summary is machine-generated.

Zygote intra-Fallopian transfer (ZIFT) and embryo intra-Fallopian transfer (EIFT) show similar success rates for patients with repeated implantation failure. This suggests both methods are equally effective for improving reproductive outcomes in challenging cases.

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Area of Science:

Reproductive Medicine
Infertility Treatment
Assisted Reproductive Technologies

Background:

Zygote intra-Fallopian transfer (ZIFT) use is declining, with current practice reserving it for patients experiencing repeated implantation failure (RIF).
Embryo intra-Fallopian transfer (EIFT), a slight modification of ZIFT performed one day later, is sometimes utilized for practical reasons.
A direct comparison of reproductive outcomes between ZIFT and EIFT in RIF patients is warranted.

Purpose of the Study:

To compare the reproductive outcomes, specifically implantation and live birth rates, between ZIFT and EIFT procedures.
To evaluate the efficacy of tubal transfer of zygotes versus day-2 cleavage stage embryos in patients with a history of failed IVF cycles.

Main Methods:

A retrospective analysis was conducted on 176 patients with a history of repeated implantation failure (average 7.65 previous IVF cycles).
Two hundred ZIFT procedures and 73 EIFT procedures were analyzed.
Demographic, clinical parameters, oocyte retrieval, fertilization rates, and embryo transfer details were compared between the two groups.

Main Results:

Patient groups undergoing ZIFT and EIFT were comparable in terms of demographic and clinical characteristics.
Similar numbers of oocytes were retrieved and fertilized, with an average of 5.2 zygotes/embryos transferred in both groups.
Implantation rates (10.5% for ZIFT vs. 10.9% for EIFT) and live birth rates (26.5% for ZIFT vs. 24.7% for EIFT) were statistically similar between the ZIFT and EIFT groups.

Conclusions:

Tubal transfer of zygotes (ZIFT) and day-2 cleavage stage embryos (EIFT) demonstrate comparable reproductive effectiveness.
EIFT serves as a viable alternative to ZIFT for patients with repeated implantation failure, offering similar success rates.
The findings support the equal efficacy of both ZIFT and EIFT in improving pregnancy outcomes for infertile patients.