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Related Concept Videos

FDA Approved Drugs: Changes to Approved Drugs01:26

FDA Approved Drugs: Changes to Approved Drugs

Post-approval, manufacturers may modify an approved new or generic drug product. Such modifications can encompass alterations in the Active Pharmaceutical Ingredient (API), manufacturing process, formulation, batch size, manufacturing site, and container closure system (FDA Guidance for Industry, April 2004). Often, a drug product may undergo multiple changes.These modifications require careful evaluation to determine their potential impact on the drug product's identity, strength, quality,...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
Prescription, Nonprescription and Orphan Drugs01:02

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Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...

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Updated: Jul 11, 2026

Inverse Probability of Treatment Weighting (Propensity Score) using the Military Health System Data Repository and National Death Index
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Published on: January 8, 2020

Medicare part D data: major changes on the horizon.

Leslie M Greenwald1

  • 1RTI International, Baltimore, Maryland, USA. lgreenwald@rti.org

Medical Care
|October 25, 2007
PubMed
Summary

Medicare Part D administrative data offer valuable insights for health services research. However, data access for researchers is currently restricted due to sensitivity, limiting comprehensive analysis.

Area of Science:

  • Health Services Research
  • Health Informatics
  • Pharmaceutical Policy

Background:

  • Centers for Medicare and Medicaid Services (CMS) developed three administrative datasets for Medicare Part D.
  • These datasets are a valuable resource for health services researchers.
  • This paper outlines the Medicare Part D program structure and its associated databases.

Purpose of the Study:

  • To describe the structure of the Medicare Part D program and its databases.
  • To discuss the utilization of these databases for research purposes.
  • To highlight the potential and limitations of Medicare Part D data for health services research.

Main Methods:

  • Description of Medicare Part D administrative data structure.
  • Analysis of enrollment files and prescription drug event (PDE) claims data.

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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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  • Discussion of data accessibility and limitations for research.

    • Main Results:

    • Medicare Part D data include plan benefits, beneficiary enrollment, and PDE claims.
    • Enrollment data offer insights into beneficiary preferences but are limited to summary availability.
    • PDE data are detailed, beneficiary-specific, and valuable for research, but only summary prescription data are public.

    Conclusions:

    • Medicare Part D data hold significant potential for addressing health services research questions.
    • The sensitive nature of the data currently restricts researcher access.
    • Improved data accessibility is needed to fully leverage these valuable datasets for research.