Related Experiment Video
Updated: Jul 11, 2026
A Preclinical Model of Exertional Heat Stroke in Mice
Published on: July 1, 2021
Separate and combined effects of airflow and rehydration during exercise in the heat
Ricardo Mora-Rodriguez1, Juan Del Coso, Roberto Aguado-Jimenez
1University of Castilla-La Mancha, Exercise Physiology Laboratory, Toledo, Spain. Ricardo.Mora@uclm.es
Purpose:
To determine whether airflow is required to obtain the beneficial effects of rehydration (thermoregulatory and cardiovascular) during exercise in dry heat.
Methods:
Ten moderately trained (VO2max = 55 +/- 8 mL.kg(-1).min(-1)) heat acclimated males pedaled for 60 min at 60% VO2max in a hot-dry environment (36 +/- 1 degrees C; 29 +/- 2% relative humidity) on four different occasions: 1) without rehydration or forced airflow (control trial; CON); 2) rehydrating 100% of sweat losses by ingestion of a 6% carbohydrate-electrolyte solution (rehydration trial; REH); 3) receiving airflow at a velocity of 2.55 m.s(-1) (wind trial; WIND); and 4) combining airflow and rehydration (W + R).
Results:
Without airflow, rehydration alone (REH) did not lower rectal temperature below CON (39.0 +/- 0.1 vs 39.1 +/- 0.1 degrees C at 60 min; respectively). However, with airflow, rehydration reduced final rectal temperature (38.8 +/- 0.1 vs 38.5 +/- 0.1 degrees C; P < 0.05; WIND vs W + R). In the trials with wind (WIND and W + R), skin temperature was reduced by about 0.6 degrees C (P < 0.05), and heart rate drift was prevented. In the trials with rehydration (REH and W + R trials), cardiac output (CO2-rebreathing technique) was maintained higher than CON (16.5 +/- 0.4 and 17.0 +/- 0.7 vs 15.4 +/- 0.4 L.min(-1), respectively; P < 0.05).
Conclusion:
When exercising in a hot-dry environment, airflow is required for rehydration to improve thermoregulation and cardiovascular function.
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