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Updated: Jul 11, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Periodontal disease severity and systemic diseases prevalent in a Caribbean catchment area of patients
1King's College London Dental Institute, King's College Dental Hospital, Denmark Hill, London SE5 9RW, United Kingdom. mena.soory@kcl.ac.uk
Objective:
To describe associations between the prevalence of periodontal disease severity and co-existence of systemic disease(s) and a smoking habit amongst periodontal referrals in a Caribbean catchment area of patients.
Methods:
A total of 100 patients completed a medical history questionnaire and were categorized for periodontal disease severity, using clinical and radiographic parameters for association with the prevalence of systemic diseases.
Results:
Twenty-two per cent presented with moderate periodontal disease (M/F ratio: 1:2.7). 68% of patients examined presented with severe periodontal disease (M/F ratio: 1:1.35). Amongst patients of the same mean age of 48 years presenting with moderate or severe periodontal disease, there was a two-fold increase in the number of missing teeth, amongst patients with severe periodontal disease. In this category there was twice the proportion of smokers and twice the number of mobile teeth, compared with those with moderate periodontal disease. In addition, there was twice the prevalence of diabetics and three times the proportion of patients with combined systemic diseases amongst those with severe periodontal disease, compared with those presenting with moderate periodontal disease, who were predominantly hypertensive or had rheumatoid arthritis. A history of smoking, diabetes mellitus and a combined manifestation of systemic diseases appeared to be more prevalent amongst those with severe periodontal disease. All these findings were significant (p < 0.001).
Conclusion:
An association between severity of periodontal disease and co-existence of systemic diseases may have implications for a unified therapeutic strategy for health.
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