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Updated: Jul 11, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
Anaplastic carcinoma of the thyroid with chondroblastoma features mimicking papillary carcinoma: a case report
Lisa A Cerilli1, William J Frable, Michael F Spafford
1Department of Pathology, University of New Mexico, Albuquerque, New Mexico 87131, USA. lcerilli@salud.unm.edu
Background:
An unusual case of anaplastic carcinoma of the thyroid arising from a metastatic focus of papillary carcinoma.
Case:
The tumor affected a 69-year-old woman with a history of total thyroidectomy for papillary thyroid carcinoma 4 years previously. She presented with a rapidly enlarging neck mass that histologically simulated chondroblastoma. A small, embedded focus of residual follicular variant of papillary carcinoma was present. The patient died of disease 3 months later.
Conclusion:
This "chondroblastoma" variant of anaplastic thyroid carcinoma has not been reported to date.

