Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Molecular Models

Molecular Models

Physical models representing molecular architectures of chemical compounds play essential roles in understanding chemistry. The use of molecular models makes it easier to visualize the structures and shapes of atoms and molecules.

Modern Molecular Taxonomy

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...

Combination Therapies and Personalized Medicine

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

Multicompartment Models: Overview

Multicompartment Models: Overview

Multicompartment models are mathematical constructs that depict how drugs are distributed and eliminated within the body. They segment the body into several compartments, symbolizing various physiological or anatomical areas connected through drug transfer processes such as absorption, metabolism, distribution, and elimination.
These models offer a more comprehensive representation of drug behavior in the body than one-compartment models. They accommodate the complexity of drug distribution,...

Mouse Models of Cancer Study

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
The development of transgenic, knockout, and knock-in mice has led to an exponential increase in their use as model organisms in research,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Contralateral Breast Background Parenchymal Enhancement: A Physiologic Marker, not a Predictor of ER Status.

Current medical imaging·2026

Same author

The need to strengthen Australian health and social policy to support survivors of the Stolen Generations.

BMJ global health·2026

Same author

Timeliness of Care and Treatment Patterns for Pancreatic Cancer in Victoria, Australia: Comparison With Optimal Care Pathways Targets.

ANZ journal of surgery·2026

Same author

How Survivors of Colorectal Cancer Experience ctDNA Testing and Fear of Recurrence.

Psycho-oncology·2026

Same author

Systematic Review and Meta-Analysis of Current and Novel Approaches in the Management of Borderline Resectable and Locally Advanced Pancreatic Cancer.

Cancers·2026

Same author

Modifiable psychosocial factors associated with psychological distress, depression, anxiety and self-rated health among Aboriginal and Torres Strait Islander populations.

Epidemiology and psychiatric sciences·2026

Search research articles

Related Experiment Video

Updated: Jul 11, 2026

Constructing and Visualizing Models using Mime-based Machine-learning Framework

Constructing and Visualizing Models using Mime-based Machine-learning Framework

Published on: July 22, 2025

The molecular medicine informatics model (MMIM).

Marienne Hibbert¹, Peter Gibbs, Terence O'Brien

¹Melbourne Health and Ludwig Institute, University of Melbourne, Australia.

Studies in Health Technology and Informatics

|October 4, 2007

Summary

A new medical informatics infrastructure, the Molecular Medicine Informatics Model (MMIM), enables secure data sharing for research. This platform facilitates individualized treatment discovery by integrating clinical, laboratory, and genetic data across institutions.

More Related Videos

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

Related Experiment Videos

Last Updated: Jul 11, 2026

Constructing and Visualizing Models using Mime-based Machine-learning Framework

Constructing and Visualizing Models using Mime-based Machine-learning Framework

Published on: July 22, 2025

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

Area of Science:

Medical Informatics
Bioinformatics
Health IT

Background:

The convergence of life sciences, healthcare, and IT drives research into disease causation and personalized medicine.
Effective data integration is crucial for advancing medical research and clinical practice.

Purpose of the Study:

To describe the implementation and capabilities of the Molecular Medicine Informatics Model (MMIM).
To highlight MMIM's role in facilitating secure, federated data access for medical research.

Main Methods:

Implementation of a federated data integrator to create a virtual research repository.
Integration of clinical, laboratory, and genetic data from independent institutions.
Establishment of authorization and permission protocols for data access, addressing legal and ethical considerations.

Main Results:

Successful implementation of a major medical informatics infrastructure in Melbourne.
MMIM enables seamless searching and querying of integrated data across multiple organizations.
Demonstrated research outcomes in epilepsy and colorectal cancer enabled by the platform.
The platform facilitates web-accessible discovery research with robust security, IP, and privacy measures.

Conclusions:

The MMIM platform provides a secure and effective infrastructure for medical research.
It enables cross-institutional data linkage, supporting advanced research into disease and individualized treatments.
MMIM addresses critical legal, ethical, and privacy concerns for health data utilization.