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Related Concept Videos

Genetic Variation01:25

Genetic Variation

Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
Genes exist in different versions called alleles, which...
Human Genetics01:28

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
Evolutionary Relationships through Genome Comparisons02:54

Evolutionary Relationships through Genome Comparisons

Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
Behavioral Genetics and Its Designs01:23

Behavioral Genetics and Its Designs

Behavior genetics explores how genetic inheritance influences human behavior. It focuses on how genes, passed from parents to offspring, contribute to the development of behavioral traits and tendencies. This branch of genetics seeks to understand the complex interplay between inherited genetic factors and environmental influences in shaping our behaviors.
The primary methodologies used in behavior genetics include family studies, twin studies, and adoption studies, each providing unique...
Principles of Pharmacogenetics: Types of Genetic Variants01:27

Principles of Pharmacogenetics: Types of Genetic Variants

The human genome is over 99.9% identical between individuals, yet genetic differences exist at millions of bases. The human genome contains approximately 3 million variant positions per individual, many of which are heterozygous, contributing to genetic diversity and individual traits. Genetic variations include single-nucleotide polymorphisms (SNPs), insertions, deletions, and copy number variations (CNVs).SNPs, the most common variation, involve single-base changes in DNA. These can be...

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Related Experiment Video

Updated: Jul 11, 2026

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information
09:37

Navigating MARRVEL, a Web-Based Tool that Integrates Human Genomics and Model Organism Genetics Information

Published on: August 15, 2019

Building a research model for human genetic variation knowledge management.

Yulong Gu1, James Warren

  • 1Department of Computer Science, University of Auckland, Auckland, New Zealand. ygu@cs.auckland.ac.nz

Studies in Health Technology and Informatics
|October 4, 2007
PubMed
Summary

This study proposes a knowledge management (KM) model for human genetic variation (HGV) research. The model aims to improve the capture and dissemination of HGV knowledge for the global genetics community.

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Last Updated: Jul 11, 2026

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Published on: August 24, 2013

Area of Science:

  • Organizational knowledge management
  • Human genetic variation research

Background:

  • Knowledge management (KM) research examines knowledge, scope, influencing factors, and theoretical frameworks.
  • Effective KM is crucial for advancing scientific research domains.

Purpose of the Study:

  • To discuss the implications of past KM studies for the human genetic variation (HGV) research domain.
  • To present a novel HGV-KM research model.

Main Methods:

  • Literature review of organizational knowledge management studies.
  • Development of a conceptual HGV-KM research model.

Main Results:

  • The proposed HGV-KM model identifies key contextual elements, influencing factors, and KM processes.
  • The model illustrates the interrelationships among these components within HGV research.

Conclusions:

  • The HGV-KM model provides a framework for future research in this domain.
  • Application of the model can enhance the capture and dissemination of HGV knowledge, benefiting the global genetics knowledge base.