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Updated: Jul 11, 2026

A 3D Organotypic Melanoma Spheroid Skin Model

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

Primary oral malignant melanoma.

Malik Boulaadas¹, Salma Benazzou, Faissal Mourtada

¹Department of Oral and Maxillofacial Surgery, Avicenne Hospital, Rabat, Morocco.

The Journal of Craniofacial Surgery

|October 4, 2007

Summary

Malignant melanoma of the oral cavity is a rare cancer with a poor prognosis. Treatment typically involves surgical excision and adjuvant therapy, as illustrated by two new case reports and a literature review.

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Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Implantation and Evaluation of Melanoma in the Murine Choroid via Optical Coherence Tomography

Published on: December 2, 2022

Area of Science:

Oncology
Oral Pathology
Surgical Oncology

Background:

Malignant melanoma of the oral cavity is a rare and aggressive neoplasm.
It is characterized by a poor prognosis, necessitating evidence-based treatment strategies.
Current therapeutic approaches often combine surgical excision with adjuvant therapies.

Observation:

This paper presents two new cases of primary oral melanoma.
The cases highlight the clinical presentation and management of this rare malignancy.
A comprehensive review of the existing literature is included.

Findings:

The reported cases contribute to understanding the variability in primary oral melanoma presentation.
Surgical excision remains the cornerstone of treatment for localized disease.
Adjuvant therapy plays a crucial role in managing advanced or metastatic oral melanoma.

Implications:

Enhanced understanding of primary oral melanoma can improve diagnostic accuracy and treatment planning.
Further research into optimal adjuvant therapies is warranted to improve patient outcomes.
These findings underscore the importance of early detection and multidisciplinary care for oral cancers.