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Published on: April 12, 2016
Submandibular area metastasis from prostate small cell carcinoma with neuroendocrine differentiation
Wen-lin Xiao1, Fu-ting Zhou, Yuan-yong Feng
1Department of Oral and Maxillofacial Surgery, The Medical School Hospital of Qingdao University, Qingdao, the People's Republic of China.
Abstract:
Neuroendocrine differentiation in prostatic carcinomas generally confers a more aggressive clinical behavior and less favorable prognosis than usual prostatic carcinomas. In this article, we report a case of a 65-year-old man with prostatic carcinoma who had a metastasis of the submandibular area. His serum prostate-specific antigen level was reduced to below the normal range and carcinoembryonic antigen was increased. Pathologic specimens demonstrated a small cell carcinoma with neuroendocrine differentiation by immunohistochemical studies.
