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Related Experiment Videos

Lichen planus.

A S Boyd1, K H Neldner

  • 1Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock 79430.

Journal of the American Academy of Dermatology
|October 1, 1991
PubMed
Summary
This summary is machine-generated.

Lichen planus is a skin disease causing itchy, purple bumps, often on limbs. While usually self-limiting, various treatments are available for this papulosquamous condition.

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Area of Science:

  • Dermatology
  • Immunology

Background:

  • Lichen planus is a papulosquamous disease.
  • Classical presentation involves pruritic, violaceous papules on extremities of middle-aged adults.
  • Oral and genital mucous membrane involvement may occur.

Purpose of the Study:

  • To describe the classical presentation of lichen planus.
  • To outline clinical variants and potential associations.
  • To review therapeutic options.

Main Methods:

  • Literature review of clinical presentations and variants.
  • Summary of established and experimental treatments.

Main Results:

  • Classical lichen planus presents as itchy, violaceous papules.

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  • Variants include lichenoid drug eruptions and associations with systemic diseases.
  • Therapeutic options include corticosteroids, retinoids, griseofulvin, PUVA, and cyclosporine.

    • Conclusions:

    • Lichen planus is a diverse condition with variable clinical presentations.
    • The relationship between classical lichen planus and its variants/associations requires further investigation.
    • Multiple treatment modalities exist for managing lichen planus.