Related Experiment Video

Updated: Jul 11, 2026

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans
12:57

Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

Published on: January 8, 2015

Prion strains under the magnifying glass

Nathan J Cobb, Witold K Surewicz

    Nature Structural & Molecular Biology
    |October 4, 2007
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Protein Misfolding Cyclic Amplification of Prions
    10:12

    Protein Misfolding Cyclic Amplification of Prions

    Published on: November 7, 2012

    High-throughput Screening for Protein-based Inheritance in S. cerevisiae
    08:12

    High-throughput Screening for Protein-based Inheritance in S. cerevisiae

    Published on: August 8, 2017

    Related Experiment Videos

    Last Updated: Jul 11, 2026

    Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans
    12:57

    Investigating the Spreading and Toxicity of Prion-like Proteins Using the Metazoan Model Organism C. elegans

    Published on: January 8, 2015

    Protein Misfolding Cyclic Amplification of Prions
    10:12

    Protein Misfolding Cyclic Amplification of Prions

    Published on: November 7, 2012

    High-throughput Screening for Protein-based Inheritance in S. cerevisiae
    08:12

    High-throughput Screening for Protein-based Inheritance in S. cerevisiae

    Published on: August 8, 2017

    Related Concept Videos

    Amyloid Fibrils03:03

    Amyloid Fibrils

    Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
    Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining, normally used to...

    Articles linked to this work by shared authors, journal, and citation graph.

    Scaffold-client behavior and structural organization in multicomponent protein condensates as revealed by studying tau/TDP-43 droplets.

    Communications chemistry·2026

    Distinct liquid-liquid phase separation properties of end-binding proteins EB1 and EB3.

    The Journal of biological chemistry·2025

    Structural exposure of different microtubule binding domains determines the propagation and toxicity of pathogenic tau conformers in Alzheimer's disease.

    PLoS pathogens·2025

    Copper binding alters the core structure of amyloid fibrils formed by Y145Stop human prion protein.

    Physical chemistry chemical physics : PCCP·2024

    Pathological C-terminal phosphomimetic substitutions alter the mechanism of liquid-liquid phase separation of TDP-43 low complexity domain.

    Protein science : a publication of the Protein Society·2024

    Pathological C-terminal phosphomimetic substitutions alter the mechanism of liquid-liquid phase separation of TDP-43 low complexity domain.

    bioRxiv : the preprint server for biology·2024

    Nucleosomes and IDRs suppress promiscuous GCN4 binding on minichromosomes.

    Nature structural & molecular biology·2026

    Structural and molecular principles of DAMP biology.

    Nature structural & molecular biology·2026

    Distinct amyloid-β filament fold in individuals with APP Flemish mutation.

    Nature structural & molecular biology·2026

    Variant characterization in the intrinsically disordered human proteome.

    Nature structural & molecular biology·2026

    Factors modulating the assembly of human β2-adrenergic receptor-β-arrestin complexes.

    Nature structural & molecular biology·2026

    Protein thiol alterations drive pathologic liquid-liquid phase separation in the aging brain.

    Nature structural & molecular biology·2026

    Exploring the effectiveness and awareness of Anki flashcard application on medical student's academic performance: a cross-sectional study from Saudi Arabia.

    Frontiers in medicine·2026

    A Multi-Scale Adaptive EEG Feature Selection and Weighting Method for Mental Workload Estimation in Rapid Serial Visual Presentation.

    IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2026

    Introducing GalaxyR: an easy-to-use R implementation of the Galaxy API.

    BMC bioinformatics·2026

    Amplification of computational power by the multiplication of bacteria exploring microfluidic networks encoding mathematical problems.

    Microsystems & nanoengineering·2026

    fast-nnt: fast, reproducible, and scalable neighbour network analysis in R, Python, and CLI.

    Bioinformatics (Oxford, England)·2026

    pix2pixHDv2: Efficient Panoramic Dental Image Synthesis with Minimal Artifacts and Computational Overhead.

    Journal of imaging informatics in medicine·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us