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Direct-Coupled Electroretinogram (DC-ERG) for Recording the Light-Evoked Electrical Responses of the Mouse Retinal Pigment Epithelium
Published on: July 14, 2020
Electronegative electroretinogram associated with topiramate toxicity and vitelliform maculopathy
Irena Tsui1, Daniel Casper, Chai Lin Chou
1Brown Glaucoma Laboratory at Edward S. Harkness Eye Institute, Columbia University, New York, NY 10032, USA. irena.tsui@gmail.com
Documenta Ophthalmologica. Advances in Ophthalmology
|October 4, 2007
Abstract:
Topiramate is known to cause ocular side effects such as refractive changes and angle closure. We describe a patient with an electronegative electroretinogram (ERG) which may have been related to topiramate use. Electronegative ERG's have been associated with other drugs in humans as well as topiramate use in rabbits. However, this would be the first suggestion of causality in humans.

