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Fundus albipunctatus in a patient with achondroplasia

Rajiv Garg1, Noopur Gupta, Pamela D'Souza

  • 1Department of Ophthalmology, Lady Hardinge Medical College, New Delhi, India.

Journal of Pediatric Ophthalmology and Strabismus
|October 5, 2007
PubMed

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Esophageal achalasia is a chronic neurogenic disorder characterized by impaired relaxation of the lower esophageal sphincter (LES) and absent or ineffective peristalsis in the distal esophagus. This leads to a functional obstruction without a physical blockage, despite significant disruption of esophageal motility.EtiologyAchalasia is caused by degeneration of the myenteric (Auerbach's) plexus, specifically the loss of inhibitory ganglion cells that produce vasoactive intestinal peptide (VIP)...