Related Experiment Video
Updated: Jul 11, 2026
07:30
Learning Modern Laryngeal Surgery in a Dissection Laboratory
Published on: March 18, 2020
Conservative laser microsurgery for T1 glottic carcinoma.
M Manola1, L Moscillo, G Costa
1Maxillo-Facial and ENT Department, G. Pascale National Institute of Tumors, Naples, Italy. marcomanola@yahoo.it
Auris, Nasus, Larynx
|October 5, 2007
Summary
Partial or complete cordectomy for T1 glottic carcinoma is a safe oncological procedure with high local control rates. The anterior vocal cord is the most frequently involved site, requiring careful margin assessment.
Area of Science:
- Otolaryngology
- Oncology
- Laser Surgery
Background:
- T1 glottic carcinoma presents a treatment challenge.
- Endoscopic CO(2) laser excision is a potential therapeutic option.
- Assessing oncological safety and margin involvement is crucial.
Purpose of the Study:
- To evaluate the oncological safety of partial or complete cordectomy for T1 glottic carcinoma.
- To analyze surgical margins and anterior commissure involvement.
- To determine local and ultimate tumor control rates.
Main Methods:
- Endoscopic CO(2) laser excision for 31 T1 glottic carcinomas.
- Inclusion of 1-2mm free margins, with additional biopsies if needed.
- Pathological measurement of lesion infiltration and distance from margins.
Main Results:
- 95% local and 100% ultimate control at 36 months.
- 90.4% complete resection; 9.6% re-resection due to positive margins.
- Anterior vocal cord most frequently involved (83.9%), particularly the anterior third (61.3%).
Conclusions:
- Partial or complete cordectomy with narrow free margins is oncologically safe for T1 glottic carcinoma.
- Careful assessment of margins and anterior commissure involvement is essential.
- High rates of local and ultimate tumor control can be achieved.