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Updated: Jun 22, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

microRNAs join the p53 network--another piece in the tumour-suppression puzzle

Lin He1, Xingyue He, Scott W Lowe

  • 1Watson School of Biological Sciences, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.

Nature Reviews. Cancer
|October 5, 2007
PubMed

Insights

The microRNA 34 (miR-34) family is directly targeted by the tumor suppressor p53. Activating miR-34 mimics p53's tumor-suppressing functions, highlighting its role in cancer development.

Area of Science:

  • Molecular Biology
  • Genetics
  • Cancer Research

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