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Published on: July 31, 2017
Children and autism--Part 1--recognition and pharmacological management
Manya Angley1, Robyn Young, David Ellis
1Quality Use of Medicines and Pharmacy Research Centre, Sansom Institute, School of Pharmacy and Medical Sciences, University of South Australia, and Women's and Children's Hospital, Adelaide, South Australia, Australia. manya.angley@unisa.edu.au
Insights
General practitioners can help identify autism spectrum disorder (ASD) early, leading to crucial support and improved outcomes. Early intervention and careful monitoring of treatments are key for children with autism.
Area of Science:
- Neurodevelopmental disorders
- Pediatric medicine
- Clinical psychology
Background:
- Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder with varied causes and outcomes.
- Genetic, nutritional, and environmental factors influence ASD etiology.
- Early recognition and intervention are critical for improving developmental trajectories.
Observation:
- General practitioners (GPs) play a vital role in recognizing potential cases of ASD.
- Formal diagnosis facilitates timely access to essential support services.
- Limited evidence exists regarding psychotropic medication efficacy and adverse effects in young individuals with ASD.
Findings:
- Antipsychotic medication use in ASD populations is increasing.
- Vigilant monitoring for adverse effects of psychotropic medications is crucial.
- Behavioral interventions, environmental modifications, and understanding are primary management strategies.
Implications:
- Early screening by GPs can significantly improve outcomes for children with ASD.
- A combined approach of behavioral and pharmacological interventions may benefit children with challenging behaviors.
- Further research is needed to establish evidence-based psychotropic treatment guidelines for ASD.
Background:
Autism is a neurodevelopmental disorder characterized by complex aetiology, variable presentation and widely divergent outcomes. It is clear that an individual's intrinsic genetic susceptibility, health, nutritional status and environmental exposures all contribute to the aetiology of autism.
Objective:
This article aims to assist the general practitioner in recognizing and managing a child with an autistic disorder.
Discussion:
Screening for autism by the GP can lead to referral for a formal diagnosis, enabling much needed support at an early stage of development, which can improve outcomes for the individual. Currently, evidence for psychotropic use and awareness of adverse effects in young people with autism is limited. Antipsychotic medications are increasingly used in people with autism and the importance of monitoring for adverse effects is paramount. Primary strategies for dealing with children with autism are understanding, environmental modification and behavioural interventions. Combined with these, pharmacological interventions may have benefits for children with autism with extreme or challenging behaviours.
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