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Updated: Jul 11, 2026
Observation and Analysis of Blinking Surface-enhanced Raman Scattering
Published on: January 11, 2018
Statistics of single-molecule surface enhanced Raman scattering signals: fluctuation analysis with multiple analyte
P G Etchegoin1, M Meyer, E Blackie
1The MacDiarmid Institute for Advanced Materials and Nanotechnology, School of Chemical and Physical Sciences, Victoria University of Wellington, P.O. Box 600 Wellington, New Zealand. Pablo.Etchegoin@vuw.ac.nz
Abstract:
The mathematical background, based on a variation of the principal component analysis (PCA) method, is developed for the understanding of fluctuating multiple analyte single-molecule (SM) surface enhanced Raman scattering (SERS) signals; with emphasis on the bianalyte SERS technique developed recently. The method and its significance are presented to provide a systematic framework with which several aspects of the statistics of SM-SERS signals can be analyzed in general. We also apply the method to a concrete example of bianalyte statistics in silver colloidal solutions and discuss related topics around experimental issues and the interpretation of single-molecule SERS data.
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