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[Endogenous candida endophthalmitis: a new therapy].
1Augenabteilung der Landeskrankenanstalten Salzburg.
Klinische Monatsblatter Fur Augenheilkunde
|December 1, 1991
Summary
A patient with vision loss due to Candida endophthalmitis (ECE) achieved successful treatment with Fluconazole when standard antifungals were not an option due to complications from colitis ulcerosa surgery.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Gastroenterology
Background:
- A patient with colitis ulcerosa underwent abdominal surgery, subsequently developing panuveitis under immunosuppression.
- This led to vision loss in one eye and progressive vitritis in the other.
Observation:
- The second eye showed increasing vitritis, leading to the diagnosis of endogenous Candida endophthalmitis (ECE) post-vitrectomy.
- The patient had a pathological blood-picture and severe cholestasis, precluding systemic administration of common antifungal medications.
Findings:
- Successful treatment of ECE was achieved using Fluconazole (Diflucan).
- This represents a novel application of Fluconazole in this specific clinical context.
Implications:
- Fluconazole can be a viable therapeutic option for endogenous Candida endophthalmitis in patients with contraindications to standard antifungals.
- This case highlights the importance of considering alternative antifungal strategies in complex patient cases.