Recent developments in idiotypic network theory

R J De Boer1

  • 1Bioinformatica, University of Utrecht, The Netherlands.

A recent class of mathematical models of the immune network is reviewed. The models in this class are based upon the bell-shaped activation function that is known to be characteristic for receptor cross-linking. These network models have a large number of self-regulatory properties. This review discusses of number of these properties, i.e. immunological memory, suppression, and repertoire selection.

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